Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
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ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
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Advances in Clinical and Experimental Medicine

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doi: 10.17219/acem/134202

Publication type: original article

Language: English

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PRF versus xenograft in sinus augmentation in case of HA-coating implant placement: A 36-months retrospective study

Sebastian Dominiak1,C,D,E,F, Ewa Karuga-Kuźniewska2,C, Paweł Popecki1,E, Paweł Kubasiewicz-Ross1,A,B,C,D,E,F

1 Department of Oral Surgery, Wroclaw Medical University, Poland

2 Department of Epizootiology and Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Poland


Background. Sinus lift with a simultaneous implant placement in the residual maxilla is a common technique used worldwide. Nevertheless, choosing an ideal grafting material remains an object of dispute. The use of an autologous blood-derived graft, known as platelet rich fibrin (PRF), has not yet been recognized to be as good as xenografts and alloplastic materials. However, initial results have been promising.
Objectives. To conduct a clinical and radiological comparison of implantation with a simultaneous sinus lift using xenograft or PRF clots.
Material and Methods. Thirty sinus lifts with simultaneous implantation were conducted using a lateral window approach and the tent pole technique, with xenograft (group 1 (G1)) or PRF (group 2 (G2)) as a filling material. To be included in the study, patients must have had an alveolar ridge height of 4–5 mm, no signs of inflammatory processes, good oral hygiene, and no other grafting procedures performed in region of implant insertion. In each case, the measurements taken were probing pocket depth (PPD), height of keratinized tissue (HKT), clinical attachment level (CAL), recession depth/width (RD/RW), and, on panoramic X-rays, marginal bone loss (MBL), grafted sinus high (GSH), and bone gain (BG). Preand post-operative treatment was applied to reduce the chance of infection.
Results. During the study, 30 implants (hydroxyapatite-coated implants manufactured by SGS – 10 mm in length and 4.2 mm in diameter) were placed. The survival rate of implants in both groups was 100% with no implant mobility, pain, paresthesia, or inflammatory processes in the direct vicinity of the implants observed, except in 1 patient. After 36 months of follow-up, the radiological assessments for G1 were: GSH 4.5 mm, MBL 0.46 mm and BG 4.53 mm; and for G2: 3.4 mm, 0.6 mm and 3.4 mm, respectively. Results of the clinical measurements were for G1: HKT after 36 months (HKT36) 2.46 mm, CAL 0.47 mm and PPD 2 mm; and for G2: HKT36 3.13 mm, CAL 0.6 mm and PPD 2.07 mm.
Conclusion. After 3 years of follow-up, the results of sinus lifting solely using PRF with simultaneous implantation were promising, especially in terms of soft tissue management. Therefore, PRF can be regarded as an alternative to previously used materials.

Key words

implant, PRF, sinus lift, growth factors, hydroxyapatite-coated implants

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