Advances in Clinical and Experimental Medicine
2014, vol. 23, nr 1, January-February, p. 5–7
Publication type: editorial article
Pyogenic Granuloma of the Lip – Treatment with Carbon Dioxide Slush Cryosurgery as an Approach in a Resource-Poor Country
1 Dermatology, Taiz University School of Medicine, Taiz, Yemen and Dermatology and Pediatrics, Rutgers University New Jersey Medical School, Newark, New Jersey, USA
Pyogenic granuloma (PG) is a benign vascular neoplasm most often evident as a rapidly developing solitary, sessile, or polypoid vascular nodule or tumor prone to ulceration or hemorrhage. Bleeding may be episodic, copious, and refractory to pressure, mandating treatment, particularly when on the lip. We describe a 14-year-old adolescent with a PG of the lower lip that responded to carbon dioxide slush cryosurgery, an option that may be of considerable value in a resource-poor country.
pyogenic granuloma, vascular neoplasm, cryosurgery, Yemen.
- Lin RL, Janniger CK: Pyogenic granuloma. Cutis 2004, 74, 229–233.
- Ghodsi SZ, Raziei M, Taheri A, Karami M, Mansoori P, Farnaghi F: Comparison of cryotherapy and curettage for the treatment of pyogenic granuloma: a randomized trial. Br J Dermatol 2006, 154, 671–675.
- Edalatkhah H, Mohebbipoor AR, Egtedari F: Comparison of cryosurgery and electrocautery in pyogenic granuloma. Iranian J Dermatol 2006, 9, 127–131.
- Patrice SJ, Wiss K, Mulliken JB: Pyogenic granuloma (lobular capillary hemangioma): a clinicopathologic study of 178 cases. Pediatr Dermatol 1991, 8, 267–276.
- Kuflik EG: Cryosurgery updated. J Am Acad Dermatol 1994, 31, 925–944, quiz 944–946.
- Al-Qubati Y, Janniger EJ, Schwartz RA: old World cutaneous leishmaniasis: cryosurgery using carbon dioxide slush in a resource-poor country. Int J Dermatol 2012, 5, 1217–1220.
- Hartzell MB: Granuloma pyogenicum (Botryomycosis of French authors.) J Cutan Dis 1904, 22, 520–525.
- Michelson HE: Granuloma pyogenicum: a clinical and histologic review of twenty-nine cases. Arch Dermatol Syphil 1925, 12, 492–505.
- Davies MG, Barton SP, Atai F, Marks R: The abnormal dermis in pyogenic granuloma: Histochemical and ultrastructural observations. J Am Acad Dermatol 1980, 2, 132–142.
- Kumar Ghosh S, Bandyopadhyay D: Granuloma pyogenicum as a complication of decorative nose piercing: report of eight cases from eastern India. J Cutan Med Surg. 2012, 16, 197–200.
- Cecchi R, Giomi A: Pyogenic granuloma as a complication of cryosurgery for venous lake. Br J Dermatol 1999, 140, 373–374.
- Elton RF: Complications of cutaneous cryosurgery. J Am Acad Dermatol 1983, 8, 513–519.
- Rader C, Piorkowski J, Bass DM, Babigian A: Epulis gravidarum manum: pyogenic granuloma of the hand occurring in pregnant women. J Hand Surg Am 2008, 33, 263–513.
- Grimalt R, Caputo R: Symmetric pyogenic granuloma. J Am Acad Dermatol 1993, 29, 652.
- da Nova Cruz LE, Martos J: Granuloma gravidarum (pyogenic granuloma) treated with periodontal plastic surgery. Int J Gynaecol obstet 2010, 109, 73–74.
- Lawoyin JO, Lawoyin DO, Arowojolu MO, Lawoyin T, Akande OO: Prevalence of pregnancy related oral granuloma in a Nigerian population group and the possible role of contraceptives. Afr J Med Med Sci 2003, 32, 409–412.
- Saravana GH: oral pyogenic granuloma: a review of 137 cases. Br J oral Maxillofac Surg. 2009, 47, 318–319.
- Schwartz RA, Nychay SG, Janniger CK, Lambert WC: Bacillary angiomatosis: presentation of six cases, some with unusual features. Br J Dermatol 1997, 136, 60–65.
- Elmets CA, Ceilley RI: Amelanotic melanoma presenting as a pyogenic granuloma. Cutis 1980, 25, 164–168.
- Cohen PJ, Hoffmann MA, Sterry W, Schwartz RA: Melanoma. In: Skin Cancer: Recognition and Management. Ed.: Blackwell, oxford, United Kingdom, 2008, 2nd ed., 152–199.