Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 2.1
5-Year Impact Factor – 2.2
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Index Copernicus  – 161.11; MNiSW – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2007, vol. 16, nr 1, January-February, p. 7–12

Publication type: editorial article

Language: English

Impedance – Expected Progress in the Diagnosis of Gastroesophageal Reflux Disease

Impedancja – nadzieje na postęp w diagnostyce choroby refluksowej przełyku

Dorota Waśko−Czopnik1,, Wojciech Błoński1,, Johannes Lenglinger2,, Leszek Paradowski1,

1 Department of Gastroenterology and Hepatology, Silesian Piasts University of Medicine in Wrocław, Poland

2 Department of Surgery, Medical University Vienna, Vienna, Austria

Abstract

Impedance−pH, a new method for the diagnosis of gastroesophageal reflux disease, is achieving increased popularity and growing acceptance. The principle of the method is measuring the difference in electric potential between two electrodes placed on a catheter and isolated one from another. When the electric circuit is closed by ions from the surroundings, a change in resistance (i.e. impedance) occurs. This method is considered more progressive and accurate than traditional 24−hour intraesophageal pH monitoring and allows distinguishing the character of reflux depending on its chemical composition and consistency. Combining traditional pH monitoring with impedance measurement of the reflux bolus helps in determining the type of symptomatic reflux more precisely, especially when resistance to treatment or extraesophageal complications are found.

Streszczenie

Impedancja jest nową metodą diagnostyczną refluksu, która cieszy się rosnącą popularnością i ma coraz większe rzesze zwolenników. Istotą jej działania jest pomiar różnicy potencjałów elektrycznych między dwoma elektrodami umieszczonymi na cewniku i rozdzielonych izolatorem. W czasie zamknięcia obwodu elektrycznego za pomocą jonów z otoczenia dochodzi do zmian oporu (impedancji). Metoda ta jest postrzegana jako nowocześniejsza i dokładniejsza od tradycyjnej pH−metrii 24−godzinnej oraz pozwala na rozróżnienie charakteru refluksu ze względu na jego skład chemiczny i konsystencję. Połączenie tradycyjnej metody pomiaru pH treści zarzucanej z impedancją pozwala z dużo większą precyzją określić typ refluksu powodującego dolegliwości, zwłaszcza przy występowaniu oporności na leczenie lub powikłaniach pozaprzełykowych.

Key words

impedance, intraesophageal pH monitoring, gastroesophageal reflux disease, nonacid reflux

Słowa kluczowe

impedancja, pH−metria, choroba refluksowa, refluks niekwaśny

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